Protocols
KAP vs Infusion-Only: Two Models of Ketamine Care
The same molecule supports very different care models. KAP and medical-model infusion clinics serve overlapping but distinct patient needs.
Medically reviewed by: Pending medical review(draft)Last updated: June 4, 2026Evidence: Dore 2019; Drozdz 2022; clinical practice surveys
Side-by-side comparison
| Dimension | KAP | Infusion-only |
|---|---|---|
| Primary clinician | Therapist + prescriber | Anesthesiologist / psychiatrist |
| Typical modality | Sublingual or IM | IV |
| Session length | 2-3 hours | 45-60 minutes |
| Dose intent | Psychedelic / experiential | Sub-psychedelic, antidepressant |
| Frequency | Weekly to monthly | 2-3x/week induction |
| Integration built in | Yes | Usually no |
| Cost per session | $400-$1,500 | $400-$800 |
| Insurance | Therapy may bill; medication rarely covered | Rarely covered (Spravato is exception) |
What KAP adds
- Pre-session preparation focused on intentions and history.
- Therapist presence during the session for emotional safety.
- Structured integration appointments after each medicine session.
- Continuity of relationship across the arc of treatment.
What infusion-only adds
- Faster, more reliable symptom relief for severe depression.
- Medical oversight optimized for cardiovascular safety.
- More efficient for patients who already have a strong therapist elsewhere.
Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.