Glossary
Bioavailability
The fraction of an administered dose that reaches systemic circulation.
Written by: Ira ZootMedically reviewed by: Ketalux Clinical Review PanelLast updated: June 4, 2026Evidence: Educational definition
Ketamine bioavailability varies by route: intravenous ~100%, intramuscular ~93%, intranasal ~25–50%, sublingual ~24–30%, oral ~16–24%. Route selection affects onset, peak effect, and predictability.
Related terms
- Routes of administration — How ketamine is delivered: IV, IM, intranasal, sublingual, oral.
Definitions are educational and general. They are not medical advice.
Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.