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Ketalux - Ketamine Therapy Education
Glossary

Ketamine metabolism

The liver pathways that clear ketamine from the body.

Written by: Ira ZootMedically reviewed by: Ketalux Clinical Review PanelLast updated: June 4, 2026Evidence: Educational definition

Ketamine is metabolized primarily by hepatic CYP3A4 and CYP2B6 enzymes to norketamine and hydroxynorketamines. Drug interactions with CYP3A4 inducers or inhibitors can alter exposure and should be reviewed pre-treatment.

Related terms

Definitions are educational and general. They are not medical advice.

Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.