Response vs. remission
Two distinct clinical endpoints in depression treatment.
Response is typically a ≥50% reduction in symptom severity; remission is a return to a near-symptom-free state (e.g., MADRS ≤10 or PHQ-9 <5). Ketamine achieves response faster than SSRIs, though sustained remission usually requires maintenance.
Related terms
- MADRS — Clinician-rated depression severity scale.
- PHQ-9 — A widely used self-report depression screening tool.
Definitions are educational and general. They are not medical advice.
Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.