Modalities
Intramuscular (IM) Ketamine
IM ketamine is often favored when the clinical goal is a deeper, more psycholytic experience for therapeutic processing.
Medically reviewed by: Pending medical review(draft)Last updated: June 4, 2026Evidence: Synthesis of KAP clinical literature
Profile
- Bioavailability: ~93%.
- Onset: 5–10 minutes.
- Duration of acute effects: 45–90 minutes.
- Titration: none after injection.
- Setting: medical or KAP clinic with monitoring.
Strengths
- Lower equipment overhead than IV.
- Often paired with psychotherapy (KAP) at higher doses.
- Cost typically below IV per session.
Trade-offs
- No real-time dose control once injected.
- Smaller depression-specific evidence base than IV.
- Experience can be more intense — appropriate screening matters.
Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.