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Ketalux
Neuroimaging & Brain Network Research

Imperial College London and ketamine research

Leading research on how ketamine and related compounds reshape brain activity and connectivity.

Medically reviewed by: Pending medical review(draft)Last updated: May 18, 2026Evidence: Institutional research summary

Overview

Imperial College London's Centre for Psychedelic Research is internationally recognized for neuroimaging work showing how rapid-acting compounds modulate the default mode network and large-scale brain connectivity — providing a mechanistic window into how patients experience therapeutic effects.

Key contributions

  • Brain imaging studies during and after ketamine administration
  • Research on default mode network changes
  • Comparative neuroscience across rapid-acting compounds
  • Translational work linking brain dynamics to clinical outcomes

Selected studies

Default mode network connectivity following rapid-acting antidepressants

NeuroImage · 2020

fMRI evidence of altered network connectivity correlating with symptom improvement.

Visit the institution

Learn more directly from Imperial College London at https://www.imperial.ac.uk/psychedelic-research-centre/.

Location: London, United Kingdom. Studies listed here are representative and not exhaustive. For full literature, consult PubMed or the institution's own publications.

Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.