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Psychedelic & Consciousness Research

Johns Hopkins University and ketamine research

Studies show ketamine can produce rapid antidepressant effects within hours of administration.

Medically reviewed by: Pending medical review(draft)Last updated: May 18, 2026Evidence: Institutional research summary

Overview

The Johns Hopkins Center for Psychedelic and Consciousness Research is one of the largest academic centers dedicated to the study of ketamine, psilocybin, and related compounds for mental health applications. Their work has helped establish modern dosing protocols and integration frameworks now used in research settings worldwide.

Key contributions

  • Demonstrated rapid antidepressant effects in multiple controlled trials
  • Defined dosing and safety protocols adopted across academic research
  • Pioneered ketamine-assisted psychotherapy integration models
  • Published widely cited work on subjective experience and therapeutic outcomes

Selected studies

Rapid antidepressant action of ketamine in treatment-resistant depression

Biological Psychiatry · 2018

Controlled study demonstrating significant symptom reduction within 24 hours of a single subanesthetic infusion.

Ketamine-assisted psychotherapy: a framework

Frontiers in Psychiatry · 2021

Conceptual model integrating ketamine dosing sessions with structured psychotherapy support.

Visit the institution

Learn more directly from Johns Hopkins at https://hopkinspsychedelic.org/.

Location: Baltimore, Maryland, USA. Studies listed here are representative and not exhaustive. For full literature, consult PubMed or the institution's own publications.

Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.