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Ketalux - Ketamine Therapy Education
Glossary

AMPA receptor

A glutamate receptor implicated in ketamine's downstream effects.

Medically reviewed by: Pending medical review(draft)Last updated: June 4, 2026Evidence: Educational definition

AMPA receptors mediate fast excitatory transmission. Ketamine-induced glutamate surges increase AMPA signaling, which contributes to synaptic plasticity and is thought to underlie part of the antidepressant response.

Related terms

  • Glutamate — The brain's primary excitatory neurotransmitter.
  • NMDA receptor — A glutamate receptor central to ketamine's mechanism of action.

Definitions are educational and general. They are not medical advice.

Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.