Glossary

BDNF

Brain-derived neurotrophic factor - a growth factor for neurons.

Medically reviewed by: Pending medical review(draft)Last updated: June 4, 2026Evidence: Educational definition

BDNF supports neuronal survival, synaptic growth, and plasticity. Ketamine and other rapid-acting antidepressants increase BDNF expression, which is one proposed mechanism for durable mood effects.

Related terms

Neuroplasticity — The brain's capacity to reorganize structure and function.
Synaptogenesis — The formation of new synaptic connections.

Definitions are educational and general. They are not medical advice.

Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.