Zarate et al. 2006 - replication in TRD
A randomized trial of an NMDA antagonist in treatment-resistant major depression
This page has been written and edited by the publisher. It has not been reviewed by a licensed clinician.
Key findings
- 71% of patients met response criteria within 24 hours
- 35% maintained response at 7 days
- Established TRD as a target population
Limitations
- Small sample
- Single dose
- Short follow-up
Publisher and editor of Ketalux, based in Chicago, Illinois. Ira is a ketamine therapy patient, not a clinician. This is editorial review, not medical review: Ira is not a licensed clinician and does not provide diagnosis or medical care. Ketalux does not accept compensation from providers in exchange for favorable editorial coverage, evidence ratings, recommendations, patient referrals, or organic provider ranking. Read the full publisher disclosure →
Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.