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Ketalux - Ketamine Therapy Education
Research Library

Ketamine Research in Acute Suicidal Ideation

One of the most clinically meaningful findings in modern psychiatry.

Medically reviewed by: Pending medical review(draft)Last updated: June 6, 2026Evidence: Wilkinson 2018; DiazGranados 2010; Murrough 2015

Findings

  • Rapid (within hours) reduction in suicidal ideation in TRD samples.
  • Effect appears partially independent of broader depression response.
  • Effect duration variable — days to weeks without further intervention.

Clinical context

Ketamine for acute suicidality is a bridge, not a destination. Hospitalization, safety planning, and ongoing care remain central.

Crisis resources

If you or someone you love is in crisis, call or text 988 (US) or visit our crisis resources page.

Educational content only. Not medical advice. Discuss any treatment decisions with a qualified clinician.

Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.