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Glossary

SSRI

Selective serotonin reuptake inhibitor - a class of antidepressants.

Written by: Ira ZootMedical review status: Not yet clinically reviewed.Last updated: June 4, 2026Evidence: Educational definition

This page has been written and edited by the publisher. It has not been reviewed by a licensed clinician.

SSRIs increase serotonin availability and are first-line for many depressive and anxiety disorders. Onset takes weeks; side effects can include sexual dysfunction, GI symptoms, and emotional blunting.

Related terms

Definitions are educational and general. They are not medical advice.

About the author

Publisher and editor of Ketalux, based in Chicago, Illinois. Ira is a ketamine therapy patient, not a clinician. This is editorial review, not medical review: Ira is not a licensed clinician and does not provide diagnosis or medical care. Ketalux does not accept compensation from providers in exchange for favorable editorial coverage, evidence ratings, recommendations, patient referrals, or organic provider ranking. Read the full publisher disclosure →

Educational use only. The content on this page is provided for general educational purposes and does not constitute medical advice, diagnosis, or treatment. Ketamine and related therapies carry risks and are appropriate only under qualified medical supervision. Always consult a licensed healthcare professional about your individual situation. Information may change as research evolves.